| Catalogue number | C262828 |
| Chemical name | ZM 447439 |
| CAS Number | 331771-20-1 |
| Synonyms | N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide; |
| Molecular Weight | C28H31N5O4 |
| Formula | 513.59 |
| Purity | 98% |
| Physical Description | Pale Yellow Solid |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | It is a potent and selective inhibitor of Aurora B kinase. Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail. It induces apoptosos in Hep2 cancer cells and in acute myeloid leukemia cell lines but its propensity to induce polyploidy does not inevitably result in apoptosis. |
| References | Ditchfield, C., et al.: J. Cell Biol., 161, 267 (2003), Long, Z.J., et al.: J. Cell Cycle, 7, 1473 (2008), Walsby, E., et al.: Haematologica, 93, 662 (2008), |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
| Size | Price(USD) | Discount |
| 1mg | $45.00 | 10% OFF |
| 10mg | $75.00 | 10% OFF |
| 50mg | $275.00 | 10% OFF |
| 2mg | $55.00 | 10% OFF |
| 25mg | $150.00 | 10% OFF |
| 100mg | $525.00 | 10% OFF |
Orders by E-mail
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To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
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Sent to your order to our email: info@coompo.com
To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
Discount Request
If you have any questions about discounts or dealer discount, please send us a message. We will be glad to help.
