URB602

Catalogue number C261831
Chemical nameURB602
CAS Number565460-15-3
SynonymsBiphenyl-3-yl Carbamic Acid, Cyclohexyl Ester; N-[1,1’-Biphenyl]-3-yl-carbamic Acid Cyclohexyl Ester
Molecular WeightC18H21NO2
Formula295.38
Purity98%
Physical DescriptionOff-White Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsURB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 µM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 µM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
ReferencesHohmann, A.G., et al.: Nature, 435, 1108 (2005), Suplita, R.L., et al.: Neuropharmacol., Nov. 25 (epub), (2005)
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URB602
Price(USD)
SizePrice(USD)Discount
50mg$125.0010% OFF
500mg$1000.0010% OFF
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