UK-356618

Catalogue number C261750
Chemical nameUK-356618
CAS Number230961-08-7
Synonyms(2R)-N1-[(1S)-2,2-Dimethyl-1-[[[(1R)-1-phenylethyl]amino]carbonyl]propyl]-N4-hydroxy-2-[3-(2-methyl[1,1’-biphenyl]-4-yl)propyl]butanediamide; UK 356618; PF-03890101;
Molecular WeightC34H43N3O4
Formula557.72
Purity98%
Physical DescriptionBeige Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsPotent and selective inhibitor of matrix metalloprotease-3 (MMP-3) (IC50 = 5.9 nM). Displays selectivity over a range of MMPs (IC50 values are 73, 840, 1790, 1900 and 51000 for MMP-13, MMP-9, MMP-2, MMP-14 and MMP-1 respectively).
ReferencesFray, M.J. et al.: Bioorg. Med. Chem. Lett., 11, 571 (2001); Fray, M.J. et al.: J. Med. Chem., 46, 3514 (2003);
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UK-356618
Price(USD)
SizePrice(USD)Discount
5mg$65.0010% OFF
25mg$245.0010% OFF
100mg$795.0010% OFF
10mg$110.0010% OFF
50mg$435.0010% OFF
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