Toceranib

Catalogue number C259255
Chemical nameToceranib
CAS Number356068-94-5
Synonyms5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide; 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-(Pyrrolidin-1-yl)ethyl)ami
Molecular WeightC22H25FN4O2
Formula396.46
Purity98%
Physical DescriptionDark Yellow Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsToceranib is a multitargeted indolinone receptor tyrosine kinase (RTK) inhibitor. Toceranib exhibited activity against a variety of spontaneous malignancies in canine such as mast cell tumors, mixed mammary carcinomas, soft tissue sarcomas, and multiple myeloma.
ReferencesLondon, C.A. et al.: Clin. Cancer Res., 9, 2755 (2003); Zavodovskaya, R. et al.: Am. J. vVt. Res., 67, 633 (2006); Malone, E.K. et al.: Vet. Comp. Oncol., 8, 209 (2010);
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Toceranib
Price(USD)
SizePrice(USD)Discount
1mg$45.0010% OFF
10mg$205.0010% OFF
5mg$110.0010% OFF
50mg$875.0010% OFF
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