| Catalogue number | C108604 |
| Chemical name | Theaflavin |
| CAS Number | 4670-05-7 |
| Synonyms | 3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-2-yl]-6-benzo[7]annulenone |
| Molecular Weight | C29H24O12 |
| Formula | 564.4 |
| Purity | 98% |
| Physical Description | Powder |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | Theaflavins have recognized medicinal benefits, and scientists have studied their positive effects on cardiovascular health, cancer, the immune system, metabolism, diabetes, and other areas. Theaflavin are antioxidant polyphenols that are formed from flavan-3-ols such as in tea leaves. Theaflavin can inhibit HIV-1 replication with multiple mechanisms of action. Theaflavins and Thearubigins compounds found in black teas penetrate the blood brain barrier, and have been shown to be effective against dementia in aging as well as AIDS related dementia plaques in vitro. Theaflavins have also been found to reduce blood cholesterol levels in human trials, both total and LDL.theaflavins are found to reduce angiogenesis, which is implicated in non-liquid cancers, an area of intense current research, by decreasing vascular endothelial growth factor production and receptor phosphorylation. Theaflavin as mimics the effects of insulin/IGF-1 action on mammalian FOXO1a, which is involved in longevity and aging. Theaflavin inhibited tumor necrosis factor-alpha mediated Interleukin-8 gene expression, as measured by luciferase assay and Northern blot analysis, at concentrations of 10 and 30 microg/mL. Theaflavins have differential inhibitory activity in cancer cell lines and has the potential to be used individually for functional food applications and for therapy targeting specific cancer treatments. The most active theaflavin (TF2A) is a promising compound that can be used as a drug or a template for drug synthesis for anticancer research. |
| References | 1. Magn. Reson. Chem., 1995, 33(7), 549-552. 2. European Food Research and Technology, 2004, 218(5), 442-447. 3. Arch. Intern. Med., 2003, 163(12), 1448-1453. 4. Biochim. Biophys. Acta, 2005, 1723 (1-3), 270–281. |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
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| 5mg | Inquiry | N/A |
| 10mg | Inquiry | N/A |
| 25mg | Inquiry | N/A |
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Sent to your order to our email: info@coompo.com
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