Teprenone

Catalogue number C257939
Chemical nameTeprenone
CAS Number6809-52-5
Synonyms6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one; Geranylgeranylacetone; Selbex; E 0671; E 36U31; GGA
Molecular WeightC23H38O
Formula330.55
Purity98%
Physical DescriptionClear Pale Yellow Oil
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsAn anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
ReferencesMurakami, M., et al.: Arzneim.-Forsch., 31, 799 (1981), Nishizawa, Y., et al.: Xenobiotica, 17, 575 (1987),
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Teprenone
Price(USD)
SizePrice(USD)Discount
5mg$45.0010% OFF
25mg$65.0010% OFF
5g$125.0010% OFF
10mg$50.0010% OFF
50mg$95.0010% OFF
50g$895.0010% OFF
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