Tandospirone-d8

Catalogue number C257646
Chemical nameTandospirone-d8
CAS Number1794835-73-6
Synonyms(3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione; (3aα,4β,7β,7aα)-Hexahydro-2-[4-[4-(2- pyrimidinyl)-1-(piperazinyl-d8)]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dio
Molecular WeightC21H21D8N5O2
Formula391.54
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsLabelled Tandospirone (T006430). Tandospirone is a 5HT1A receptor partial agonist. Studies indicate that tandospirone significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. The potency of Tandospirone is equal to that of buspirone and approximate one-half that of diazepam. The potency of Tandospirone at dopamine antagonistic action is less than 1/4 that of buspirone.
ReferencesSeymour, P.A., et al.: Prog. Clin. Biol. Res., 361, 453 (1990), Evans, S.M., et al.: J. Pharmacol. Exp. Ther., 271, 683 (1994),
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Tandospirone-d8
Price(USD)
SizePrice(USD)Discount
2.5mg$140.0010% OFF
25mg$1120.0010% OFF
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