THZ1

Catalogue number C259074
Chemical nameTHZ1
CAS Number1604810-83-4
SynonymsN-[3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-benzamide
Molecular WeightC31H28ClN7O2
Formula566.05
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsTHZ1 is a covalent cyclin-dependent kinases 7 (CDK7) inhibitor. It has the ability to target a remote cysteine residue located outside of the canonical kinase domain, providing a means of achieving selectivity for CDK7.
ReferencesKwiatkowski, N., et al.: Nature, 511, 616 (2014)
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THZ1
Price(USD)
SizePrice(USD)Discount
.5mg$215.0010% OFF
10mg$3750.0010% OFF
2.5mg$995.0010% OFF
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