Succinimidyl-6-(biotinamido) Hexanoate

Catalogue number C257244
Chemical nameSuccinimidyl-6-(biotinamido) Hexanoate
CAS Number72040-63-2
SynonymsNHS-LC-BIOTIN
Molecular WeightC20H30N4O6S
Formula454.55
Purity98%
Physical DescriptionWhite to Off-White Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsSuccinimidyl-6-(biotinamido) Hexanoate is a biotinylation reagent incorporating an aminocaproyl “spacer”. This can reduce the steric hindrance in binding avidin to some biotinylated compounds when used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin Capture System. This system avoids the direct interaction of a captured antibody with solid surfaces, such as plastics, which may reduce antigenicity. It has also been used to enhance the detection of DNA on nitrocellulose. Has also been used as a cell surface labelling reagent
ReferencesHofmann, K., et al.: Biochemistry, 21, 978 (1982); Leary, J.J., et al.: P. Natl. Acad. Sci. USA, 80, 4045, (1983); Suter, M., et al.: Immunology Letters, 13, 313 (1986); Gretch, D.R., et al.: Anal. Biochem., 163, 270 (1987), Burgess, T.L., et al.: J. Biol. Chem., 269 (32), 19188 (1995), Schumacher, T.N.M., et al.: Science, 271, 1854 (1996)
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Succinimidyl-6-(biotinamido) Hexanoate
Price(USD)
SizePrice(USD)Discount
10mg$50.0010% OFF
100mg$95.0010% OFF
500mg$410.0010% OFF
25mg$80.0010% OFF
250mg$225.0010% OFF
1g$740.0010% OFF
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