Catalogue number | C108665 |
Chemical name | Sodium Aescinate |
CAS Number | 20977-05-3 |
Synonyms | Sodium escinate;butanoic acid,3-(acetyloxy)-2-methyl-, (5xi,8xi,9xi,10xi,16alpha,17xi, 18xi,21beta)-16,21-epoxy-3-[[O-alpha-D-glucopyranosyl-(1->4)-O-[beta-D-xylopyranosyl- (1->2)]-beta-D-glucopyranuronosyl]oxy]-22,24-dihydroxyolean-12-en-28-yl ester, monoso dium saltthyl)phenoxy]oxane-3,4,5-triol |
Molecular Weight | C55H85O24Na |
Formula | 1153.2 |
Purity | 98% |
Physical Description | White powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Sodium aescinate (SA) has been shown to exert anti-inflammatory and antiedematous effects. The effects of SA and the possible mechanisms of SA action in rats with ALI induced by oleic acid (OA) administration. Both pre- and posttreatment with SA improved OA-induced pulmonary injury, increased P(O(2)) and SOD values, lowered IQA scores, and decreased the lung W/D ratio and MDA and MMP-9 levels in plasma and lung tissue. SA appeared to abrogate OA-induced ALI by modulating the levels of SOD, MDA, and MMP-9 in plasma and lung tissue. |
References | 1. Journal of Chinese Pharmaceutical Sciences 2004, 13(2), 87-91. 2. Exp Lung Res., 2011, 37(10), 585-599. |
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After Receiving
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