Selisistat

Catalogue number C256281
Chemical nameSelisistat
CAS Number49843-98-3
Synonyms6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide; 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic Acid Amide; EX 527
Molecular WeightC13H13ClN2O
Formula248.71
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsSelisistat is a potent and selective sirtuin 1 (SIRT1) inhibitor identified from a high throughput screen. It is more selective (200-500-fold) for SIRT1 than for SIRT2 or SIRT3 and has been shown to be a potent SIRT6 inhibitor using H3K56 deacetylation site based substrate.
ReferencesKokkonen, P., et al.: Eur. J. Pharm. Sci., 63, 71 (2014); Zhang, Y., et al.: Oncogene, 28, 445 (2009)
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Selisistat
Price(USD)
SizePrice(USD)Discount
100mg$105.0010% OFF
500mg$415.0010% OFF
250mg$225.0010% OFF
1g$800.0010% OFF
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