Saikosaponin C

Catalogue number C108864
Chemical nameSaikosaponin C
CAS Number20736-08-7
Synonyms(3beta,4alpha,16beta)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-4)-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopy ranoside
Molecular WeightC48H72O17
Formula927.1
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Saikosaponin C yielded a potent effect on inducing human umbilical vein endothelial cells (HUVECs) viability and growth. In addition to inducing endothelial cells growth, saikosaponin C also induced endothelial cells migration and capillary tube formation. The gene expression or activation of matrix metalloproteinase-2 (MMP-2), vascular endothelial growth factor (VEGF) and the p42/p44 mitogen-activated protein kinase (MAPK, ERK) that correlated with endothelial cells growth, migration and angiogenesis were also induced by saikosaponin C. saikosaponin C may have the potential for therapeutic angiogenesis but is not suitable for cancer therapy.

 

Saikosaponin C exhibits anti-HBV activity and saikosaponin D possesses potent cytotoxicity against human hepatocellular carcinoma cells.

References1. J. Sep. Sci., 2009, 32, 74-78.
2. Life Sciences, 2004, 76(7), 813-826.
3. Planta Med., 2003, 69(8), 705-709.
4. Planta Med., 1985, 51(3), 208-212.
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Saikosaponin C
Price(USD)
SizePrice(USD)Discount
5mgInquiryN/A
10mgInquiryN/A
25mgInquiryN/A
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