| Catalogue number | C255167 |
| Chemical name | RAF 265 |
| CAS Number | 927880-90-8 |
| Synonyms | CHIR 265; 1-Methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine |
| Molecular Weight | C24H16F6N6O |
| Formula | 518.41 |
| Purity | 98% |
| Physical Description | Powder |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | RAF 265 is a multikinase inhibitor that has displayed BRAF inhibiting activity in clinical trials. It could be used in the treatment of a subpopulation of human melanoma tumors. Has cytotoxic effect of on MDA-MB-231 cells. RAF265 when used with BEZ-235 inhibited ERK, PI3K signaling that reduced growth, proliferation and development of drug resistance in human thyroid cancer cells. |
| References | Su, Y. et al.: Clin. Cancer. Res., 18, 2184 (2012); Zambon, A. et al.: Bioorg. Med. Chem. Lett., 22, 789 (2012); Dittmer, A. et al.: Int. J. Oncol., 39, 689 (2011); Jin, N. et al.: Clin. Cancer. Res., 17, 6482 (2011) |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
| Size | Price(USD) | Discount |
| 5mg | $150.00 | 10% OFF |
| 25mg | $480.00 | 10% OFF |
| 10mg | $240.00 | 10% OFF |
| 100mg | $1440.00 | 10% OFF |
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To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
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