Pyroxamide

Catalogue number C254837
Chemical namePyroxamide
CAS Number382180-17-8
SynonymsN1-hydroxy-N8-3-pyridinyloctanediamide; N-hydroxy-N’-3-pyridinyloctanediamide;
Molecular WeightC13H18N3O3
Formula265.31
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsPyroamide is a histone decetylase inhibitor (HDCi), a novel class of anti-neoplastic agent that acts by enhancing acetylation of histones, promoting uncoiling of chromatin and activation of genes implicated in the regulation of cell survival such as poliferation, differentiation and apoptosis. Pyroamide is known to potently inhibits affinity purified HDAC1. Also inhibits the growth of tumor cells in vitro and in vivo. Induces p21/WAF1 expression in tumor cells.
ReferencesAparna, L.I., et al.: Intern. J. Pharma. Sci. Review. Rsch., 10, 38 (2011); Pontiki, E., et al.: Medn. Rsch. Reviews., 32, 1 (2012);
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Pyroxamide
Price(USD)
SizePrice(USD)Discount
5mg$45.0010% OFF
25mg$165.0010% OFF
250mg$1200.0010% OFF
10mg$75.0010% OFF
50mg$295.0010% OFF
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