Catalogue number |
C108764 |
Chemical name | Procyanidin B2 |
CAS Number | 29106-49-8 |
Synonyms | (2R,2’R,3R,3’R,4R)-2,2’-Bis(3,4-dihydroxyphenyl)-3,3’,4,4’-tetrahydro-[4,8’-bi-2H-1-benzopyran]-3,3’,5,5’,7,7’-hexol |
Molecular Weight | C30H26O12 |
Formula | 578.5 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Procyanidin B2 has been shown to inhibit the formation of the advanced glycation end-products pentosidine, carboxymethyllysine (CML), and methylglyoxal (MGO).
Procyanidin B-2 acts as a hair-growing factor in the murine model both in vitro and in vivo. Investigation of the effects of 1% procyanidin B-2 tonic on human hair growth after sequential use for 6 months. A double-blind clinical test involving a total of 29 subjects was performed. Nineteen men in the procyanidin B-2 group and 10 men in the placebo control group were subjected to analyses. No adverse side effects were observed in either group. The hair-growing effect was evaluated using a macrophotography technique combined with measurements of the hair diameter of clipped hairs. The increase in number of total hairs in the designated scalp area (0.5 cm square = 0.25 cm2 area) of procyanidin B-2 group subjects after the 6-month trial was significantly greater than that of the placebo control group subjects (procyanidin B-2, 6.68 +/- 5.53 (mean +/- SD)/0.25 cm2; placebo, 0.08 +/- 4.56 (mean +/- SD)/0.25 cm2; P < 0.005, two-sample t test). The increase in number of terminal hairs, which are defined as hairs more than 60 microm in diameter, in the designated area (0.5 cm square = 0.25 cm2 area) of the procyanidin B-2 group subjects after the 6-month trial was significantly greater than that of the placebo control group subjects (procyanidin B-2, 1.99 +/- 2.58 (mean +/- SD)/0.25 cm2; placebo, -0.82 +/- 3.40 (mean +/- SD)/0.25 cm2; P < 0.02, two-sample t test). Procyanidin B-2 therapy shows potential as a safe and promising cure for male pattern baldness.
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References | 1. J. Chem. Soc., Perkin Trans. 1, 1982, 1217-1221 2. J. Agric. Food Chem., 2003, 51(13), 3806-3813 3. Chinese Traditional Patent Medicine, 2007, 29(11), 1645-1647. 4. J. Agric. Food Chem., 2010, 58(11), 6692-6696. 5. Phytomedicine, 2000, 7(6), 529-536.
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Size | Price(USD) | Discount |
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10mg | Inquiry | N/A |
25mg | Inquiry | N/A |
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