Catalogue number | C108624 |
Chemical name | Podophyllotoxin |
CAS Number | 518-28-5 |
Synonyms | (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one |
Molecular Weight | C22H22O8 |
Formula | 414.4 |
Purity | 98% |
Physical Description | White cryst. |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Among the plethora of physiological activities and potential medicinal and agricultural applications, the antineoplastic and antiviral properties of podophyllotoxin congeners and their derivatives are arguably the most eminent from a pharmacological perspective. Podophyllotoxin is an antimitotic. It acts by preventing viral wart cells from dividing and multiplying. Eventually all the wart cells die and new healthy cells grow in their place. In the 1930s, doctors in New Orleans started using podophyllotoxin for the treatment of genital warts. By 1942 the first description of this practice was published in medical literature. |
References | 1. Journal of Pharmaceutical Sciences, 1986, 75(11), 1076-1080. 2. J. Med. Chem., 1986, 29(8), 1547-1550. 3. Phytochemistry, 1980, 19(7), 1527-1530. 3. Lipids, 2004, 39(2), 167-172. |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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