Pixantrone-N7-desethanamine Dihydrochloride

Catalogue number C255779
Chemical namePixantrone-N7-desethanamine Dihydrochloride
CAS NumberN/A
SynonymsN7-(Desaminoethyl)-Pixantrone Dihydrochloride; 6-Amino-9-[(2-aminoethyl)amino]-benz[g]isoquinoline-5,10-dione Dihydrochloride
Molecular WeightC15H14N4O2
Formula282.3
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsPixantrone-N7-desethanamine Dihydrochloride is an impurity of Pixantrone (P552500), an antineoplastic drug belonging to group of antitumor antibiotics. Pixantrone is an anlogue of Mitoxantrone (M373425) and is just as potent in the treatment of multiple sclerosis with fewer toxic effects on cardiac tissue. Studies suggest that Pixantrone significantly reduces amyloid beta (A beta(1-42)) neurotoxicity, a mechanism implicated in Alzheimer’s disease.
ReferencesCavalletti, E. et al.: Invest. New Drugs, 25, 187 (2007); Gonsette, R.E. et al.: J. Neurol. Sci., 223, 81 (2004); Colombo, R. et al.: Electrophoresis, 30, 1418 (2009)
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Pixantrone-N7-desethanamine Dihydrochloride
Price(USD)
SizePrice(USD)Discount
1mg$175.0010% OFF
5mg$740.0010% OFF
2.5mg$390.0010% OFF
10mg$1400.0010% OFF
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