PK 11195-d3

Catalogue number C255863
Chemical namePK 11195-d3
CAS NumberN/A
Synonyms
Molecular WeightC21H18D3ClN2O
Formula355.88
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsPK 11195-D3 is the isotope labelled analog of PK 11195 (P571500), a high affinity peripheral benzodiazepine receptor (PBR) ligand. PK 11195 has been shown to regulate protein phosphorylation in rat brain mitochondria under control of Ca2+. PK11195 promotes mitochondrial apoptosis and blocks P-glycoprotein (Pgp)-mediated drug efflux to chemosensitize cancer cells.
ReferencesAzarashvili, T. et al.: J. Neurochem., 94, 1054 (2005); Le Fur, G. et al.: Life Sci., 33, 449 (1983)
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The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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PK 11195-d3
Price(USD)
SizePrice(USD)Discount
2.5mg$150.0010% OFF
25mg$1200.0010% OFF
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