| Catalogue number | C252345 |
| Chemical name | PHA-543613 Dihydrochloride |
| CAS Number | 478148-58-2 |
| Synonyms | N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide Dihydrochloride; PHA 543613E; |
| Molecular Weight | C15H18Cl2N3O2 |
| Formula | 344.24 |
| Purity | 98% |
| Physical Description | Tan Solid |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer′s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays. |
| References | Shaffer, C.L. et al.: Drug Metab. Dispos., 35, 1188 (2007); Wishka, D.G. et al.: J. Med. Chem., 49, 4425 (2006); Acker, B.A. et al.: Bioorg. Med. Chem. Lett., 18, 3611 (2008); |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
| Size | Price(USD) | Discount |
| 5mg | $85.00 | 10% OFF |
| 25mg | $320.00 | 10% OFF |
| 100mg | $995.00 | 10% OFF |
| 10mg | $150.00 | 10% OFF |
| 50mg | $545.00 | 10% OFF |
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To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
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