Catalogue number | C252328 |
Chemical name | PF-4800567 Hydrochloride |
CAS Number | N/A |
Synonyms | 3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Hydrochloride; PF 4800567 Hydrochloride; |
Molecular Weight | C17H18Cl2N5O2 |
Formula | 396.27 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | PF 4800567 is a selective casein kinase 1ε inhibitor; displays 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively). ATP competitive. Displays minimal effect on the circadian clock. |
References | Behrend, L., et al.: Oncogene, 19, 5303 (2000), Badura, L., et al.: J. Pharmacol. Exp. Ther., 322, 730 (2007), Arora, S., et al.: Cancer Res., 69, 1910 (2009), Walton, et al.: J. Pharmacol. Exp. Ther., 330, 430 (2009), |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
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