PF-4800567 Hydrochloride

Catalogue number C252328
Chemical namePF-4800567 Hydrochloride
CAS NumberN/A
Synonyms3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Hydrochloride; PF 4800567 Hydrochloride;
Molecular WeightC17H18Cl2N5O2
Formula396.27
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsPF 4800567 is a selective casein kinase 1ε inhibitor; displays 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively). ATP competitive. Displays minimal effect on the circadian clock.
ReferencesBehrend, L., et al.: Oncogene, 19, 5303 (2000), Badura, L., et al.: J. Pharmacol. Exp. Ther., 322, 730 (2007), Arora, S., et al.: Cancer Res., 69, 1910 (2009), Walton, et al.: J. Pharmacol. Exp. Ther., 330, 430 (2009),
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PF-4800567 Hydrochloride
Price(USD)
SizePrice(USD)Discount
10mg$140.0010% OFF
100mg$1120.0010% OFF
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