Oxymatrine

Catalogue number C107841
Chemical nameOxymatrine
CAS Number16837-52-8
SynonymsAmmothamnine; Matrine N-oxide
Molecular WeightC15H24N2O2
Formula264.4
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Oxymatrine, an isolated extract from traditional Chinese herb Sophora flavescens Ait, has been traditionally used for therapy of anti-hepatitis B virus, anti-inflammation and anti-anaphylaxis.
Oxymatrine can induce apoptotic cell death of human pancreatic cancer, which might be attributed to the regulation of Bcl-2 and IAP families, release of mitochondrial cytochrome c and activation of caspase-3.


Oxymatrine may inhibit the expression of the above pro-inflammatory cytokines. Oxymatrine also inhibited expression of Substance P and NK-1R in a human model of skin inflammation, as well as acting as an agonist at mu and kappa opioid receptors.

References1. Magnetic Resonance in Chemistry, 1988, 26(3), 185-190.
2. Applied Magnetic Resonance, 2002, 23(2), 113-121.
3. Zhongguo Zhong Yao Za Zhi. 2001, 26(4), 272-274.
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Oxymatrine
Price(USD)
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