Catalogue number | C101603 |
Chemical name | Octacosyl (E)-ferulate |
CAS Number | 101959-37-9 |
Synonyms | 2-Propenoicacid, 3-(4-hydroxy-3-methoxyphenyl)-, octacosyl ester, (E)-; Erythrinasinate B |
Molecular Weight | C38H66O4 |
Formula | 586.9 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Octacosyl ferulate markedly inhibited the inflammatory activity induced by TPA in mice. The 50% inhibitory dose of octacosyl ferulate is 0.7 mg/ear on TPA-induced inflammation. Furthermore, octacosyl ferulate suppressed markedly the tumour-promoting effect of TPA on skin tumour formation following initiation with DMBA. Since protein kinase C (PK-C) was shown to be an intracellular target of TPA, effects of octacosyl ferulate on the activity of this enzyme were investigated. Octacosyl ferulate also inhibited the phosphorylation of histon III-S by PK-C in a concentration dependent manner. |
References | 1. Chemistry & Biodiversity, 2011, 8(9), 1709-1716. 2. Phytotherapy Research, 1998, 12(4), 261-265. |
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