O’Ethly-N-boc-1-oxo-3-tertbutyldimethylsilyl-D-erythro-sphingosine

Catalogue number C256855
Chemical nameO’Ethly-N-boc-1-oxo-3-tertbutyldimethylsilyl-D-erythro-sphingosine
CAS NumberN/A
Synonyms(2R,3R,E)-Ethyl 2-((tert-Butoxycarbonyl)amino)-3-((tert-butyldimethylsilyl)oxy)octadec-4-enoate; D-erythro-Sphingosine-N-tert-butyloxycarbonyl-1-oxo-3-tert-butyldimethylsilyl Ethyl Ester
Molecular WeightC31H61NO5Si
Formula555.91
Purity98%
Physical DescriptionColourless oil
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsD-erythro-Sphingosine-N-tert-butyloxycarbonyl-O-tert-butyldimethylsilyl Ethyl Ester is an intermediate formed in the synthesis of β-Galactosyl-C18-ceramide (G184960), which is a galactosylceramides that plays an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.
ReferencesMorita, M., et al.: J. Med. Chem., 38, 2176 (1995); Sakai, T., et al.: J. Med. Chem., 42, 1836 (1999)
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O’Ethly-N-boc-1-oxo-3-tertbutyldimethylsilyl-D-erythro-sphingosine
Price(USD)
SizePrice(USD)Discount
1mg$200.0010% OFF
25mg$3100.0010% OFF
5mg$775.0010% OFF
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