Nimbolide

Catalogue number C252452
Chemical nameNimbolide
CAS Number25990-37-8
Synonyms(4α,5α,6α,7α,15β,17α)-7,15:21,23-Diepoxy-6-hydroxy-4,8-dimethyl-1-oxo-18,24-dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic Αcid γ-lactone Methyl Ester; NSC 309909;
Molecular WeightC27H30O7
Formula466.52
Purity98%
Physical DescriptionLight Beige to Yellow Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsNimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong growth inhibition.
ReferencesKhalid, S., et al.: J. Nat. Prod., 52, 922 (1989), Cohen, E., et al.: J. Life Sci., 58, 1075 (1996), Moragoda, L., et al.: Anticancer Res., 21, 873 (2001), Chang, K., et al.: Biochem. Pharmacol., 67, 717 (2004), Parsels, L., et al.: Cancer Res., 64, 6588 (2004),
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Nimbolide
Price(USD)
SizePrice(USD)Discount
1mg$300.0010% OFF
10mg$2400.0010% OFF
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