NVP-BAG956

Catalogue number C250016
Chemical nameNVP-BAG956
CAS Number853910-02-8
Synonyms2-Methyl-2-[4-[2-methyl-8-[(pyridin-3-yl)ethynyl]imidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile; BAG 956; NVP-BAG 956; α,α-Dimethyl-4-[2-methyl-8-(3-pyridinylethynyl)-1H-imidazo[4,5-c]quinolin-1-yl]benzeneacetonitrile
Molecular WeightC28H21N5
Formula427.5
Purity98%
Physical DescriptionWhite Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsNVP-BAG956 acts as a rapamycin inhibitor used in the treatment of various melanomas through cell-induced apoptosis. Also used in antileukemic therapies as a dual PI3K/PDK-1 inhibitor.
ReferencesMarone, R. et al.: Mol. Canc. Res., 7, 601 (2009); Weisberg, E. et al.: Blood, 111, 3723 (2008);
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NVP-BAG956
Price(USD)
SizePrice(USD)Discount
10mg$195.0010% OFF
50mg$825.0010% OFF
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