Catalogue number | C249986 |
Chemical name | NSC 109555 |
CAS Number | 15427-93-7 |
Synonyms | 4,4’-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2,2’-[Carbonylbis(imino-4,1-phenyleneethylidyne)]bis-hydrazinecarboximidamide Dimethanesulfonate |
Molecular Weight | C21H32N10O7S2 |
Formula | 600.67 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | NSC 109555 is an inhibitor of checkpoint kinase 2 (Chk2), a serine/threonine kinase involved in the ATM-Chk2 checkpoint pathway. Drugs that target Chk2 in combination with DNA-damaging agents can be beneficial in cancer therapy. Studies in mice, rats, rabbits, dogs, and monkeys have shown that NSC 109555 displays toxic effects. A singe injection of the drug at a concentration of 12.5-25 mg/kg caused acute paralysis leading to apnea and death. |
References | Lountos, G. et al.: Protein Sci., 18, 92 (2009); Mihich, E. et al.: Canc. Res., 29, 1056 (1969) |
Guestbook |
After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
Size | Price(USD) | Discount |
10mg | $130.00 | 10% OFF |
100mg | $1080.00 | 10% OFF |
50mg | $575.00 | 10% OFF |
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To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
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