N-Trifluoroacetyliso Deacetylcolchicine

Catalogue number C260343
Chemical nameN-Trifluoroacetyliso Deacetylcolchicine
CAS Number71324-48-6
Synonyms2,2,2-Trifluoro-N-[(7S)-5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo[a]heptalen-7-yl]acetamide; N-(Trifluoroacetyl)deacetylisocolchicine;
Molecular WeightC22H22F3NO6
Formula453.41
Purity98%
Physical DescriptionTan Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsAn antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
ReferencesLunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),
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N-Trifluoroacetyliso Deacetylcolchicine
Price(USD)
SizePrice(USD)Discount
100mg$120.0010% OFF
1g$960.0010% OFF
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