N-Fmoc-D-serine

Catalogue number C214311
Chemical nameN-Fmoc-D-serine
CAS Number116861-26-8
SynonymsN-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-serine; N-(9-Fluorenylmethoxycarbonyl)-D-serine
Molecular WeightC18H17NO5
Formula327.33
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsN-Fmoc-D-serine is an N-Fmoc-protected form of D-Serine (S270975). D-Serine is a neurotransmitter that is concentrated in the mammalian brain, and is one of the very few amino acids that occur in the D- and L-configurations in significant amounts. D-Serine is an potent agonist of the N-methyl-D-aspartate (NMDA) receptor in the brain, which is associated with schizophrenia. Use of D-Serine has been considered as an additional therapy for refractory schizophrenic patients.
ReferencesHeresco-Levy, U., et al.: Biol. Psych., 57, 577 (2005); Mothet, J., et al.: Proc. Nat. Acad. Sci., 97, 4926 (2000); Snyder, S. & Kim, P.: Neurochem. Res., 25, 553 (2000); Tsai, G., et al.: Biol. Psych., 44, 1081 (1998)
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N-Fmoc-D-serine
Price(USD)
SizePrice(USD)Discount
1g$50.0010% OFF
10g$275.0010% OFF
50g$750.0010% OFF
5g$150.0010% OFF
25g$400.0010% OFF
100g$1200.0010% OFF
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