Catalogue number | C248561 |
Chemical name | Myriocin |
CAS Number | 35891-70-4 |
Synonyms | (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; [2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid; (+)-Myriocin; ISP-I; NSC 177379; Thermozymocidin; (2S,3R,4R)-(E)-2-Amino-3,4-dihydrox |
Molecular Weight | C21H38NO6 |
Formula | 401.54 |
Purity | 98% |
Physical Description | White to Off-White Solid |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine palmitoyltransferase and thus blocks the synthesis ceramide, a precursor in sphingomyelin and glycosphingolipid biosynthesis. As a result Myriocin is a useful biochemical research tool for depleting cells of sphingolipids. |
References | Miyake, Y., et al.: Biochem. Biophys. Res. Commun., 211, 396 (1995); Hidari, K.I.P.J. et al.: J. Biol. Chem., 271, 14636 (1996); Nakamura, S. et al.: J. Biol. Chem., 271, 1255 (1996); De Zélicourt, A. et al.: Planta 230, 1047 (2009); Kluepfel, D., et al.: J. Antib., 25, 109 (1972) |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
Size | Price(USD) | Discount |
1mg | $45.00 | 10% OFF |
5mg | $60.00 | 10% OFF |
25mg | $165.00 | 10% OFF |
2mg | $50.00 | 10% OFF |
10mg | $90.00 | 10% OFF |
50mg | $325.00 | 10% OFF |
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To place an order, please provide the following information.
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Sent to your order to our email: info@coompo.com
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