Catalogue number | C248035 |
Chemical name | Mono-tert-butyl Malonate |
CAS Number | 40052-13-9 |
Synonyms | Propanedioic Acid 1-(1,1-Dimethylethyl) Ester; Propanedioic acid Mono(1,1-dimethylethyl) Ester; 2-(tert-Butoxycarbonyl)acetic acid; 3-tert-Butoxy-3-oxopropanoic acid; Malonic acid mono-tert-butyl ester; Malonic acid tert-butyl monoester; tert-Butyl hydrog |
Molecular Weight | C7H12O4 |
Formula | 160.17 |
Purity | 98% |
Physical Description | liquid |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | Mono-tert-butyl Malonate is a useful synthetic intermediate. It can be used to prepare quinoline-based zinc metallo-aminopeptidase inhibitors with antimalarial activity. It can also be used to synthesize truncated aminoglycoside-CoA bisubstrate analogs via chemo- and regioselective coupling reaction of amine and thiols, as inhibitors of aminoglycoside 6’-N-acetyltransferase Ii |
References | Flipo, M., et al.: Bioorg. Med. Chem. Lett., 13, 2659 (2003); Gao, F., et al.: J. Med. Chem., 49, 5273 (2006) |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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50g | $275.00 | 10% OFF |
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