Momordicoside F1

Catalogue number C104671
Chemical nameMomordicoside F1
CAS Number81348-81-4
Synonymsb-D-Glucopyranoside,1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-17-(5-methoxy-1,5-dimethyl-3-hexenyl)-4,4,13,14-tetramethyl-5,9-(epoxymethano)-2H-cyclopenta[a]phenanthren-3-yl,[3S-[3a,5a,8a,9a,10b,13a,14b,17a(1S*,3E)]]-; 5,9-(Epoxymethano)-2H-cyclopenta[a]phenanthrene, b-D-glucopyranoside deriv.; b-D-Glucopyranoside,(3S,5R,8S,9S,10S,13R,14S,17R)-1,3,4,8,10,11,12,13,14,15,16,17-dodecahydro-17-[(1R)-5-methoxy-1,5-dimethyl-3-hexenyl]-4,4,13,14-tetramethyl-5,9-(epoxymethano)-2H-cyclopenta[a]phenanthren-3-yl
Molecular WeightC37H60O8
Formula632.9
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Antidiabetic activities.

 

Momordicosides enhanced fatty acid oxidation and glucose disposal during glucose tolerance tests in both insulin-sensitive and insulin-resistant mice. These findings indicate that cucurbitane triterpenoids, the characteristic constituents of M. charantia, may provide leads as a class of therapeutics for diabetes and obesity.

References1. Chemical and Pharmaceutical Bulletin, 2001, 49(1), 54-63.
2. Chemistry & Biology, 2008, 15(3), 263-273.
3. Journal of Medicinal Plants Research, 2009, 3(13), 1264-1269.
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Momordicoside F1
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