Metanicotine-d3

Catalogue number C245909
Chemical nameMetanicotine-d3
CAS Number220088-40-4
Synonyms(E)-N-[Methyl]-4-(3-pyridinyl)-3-buten-1-amine-d;, RJR 2403-d3; Rivanicline-d3; (E)-Metanicotine-d3
Molecular WeightC10H11D3N2
Formula165.25
Purity98%
Physical DescriptionClear Colourless Oil
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsMetanicotine-d3 is the isotope labelled analog of Metanicotine (M321250); an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer’s type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors.
ReferencesSchmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964); Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982); Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993); Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)
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Metanicotine-d3
Price(USD)
SizePrice(USD)Discount
1mg$150.0010% OFF
10mg$1200.0010% OFF
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