MK-2206 Dihydrochloride

Catalogue number C247870
Chemical nameMK-2206 Dihydrochloride
CAS Number1032350-13-2
Synonyms8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Hydrochloride;
Molecular WeightC25H23Cl2N5O
Formula480.39
Purity98%
Physical DescriptionYellow Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsAZD 6244 and MK 2206 are targeted small-molecule drugs that inhibit MEK and AKT responses. The combination of AZD6244 and MK2206 has a significant synergistic effect on tumor growth in vitro and in vivo and leads to increased survival rates in mice bearing highly aggressive human lung tumors. Antitumor agents.
ReferencesYeh, T., et al.: Clin. Cancer Res., 13, 1576 (2007), Meng, J., et al.: Cancer Biol. Ther., 8, 2073 (2009),
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MK-2206 Dihydrochloride
Price(USD)
SizePrice(USD)Discount
1mg$45.0010% OFF
10mg$150.0010% OFF
50mg$555.0010% OFF
5mg$95.0010% OFF
25mg$325.0010% OFF
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