LM 22A4

Catalogue number C241689
Chemical nameLM 22A4
CAS Number37988-18-4
SynonymsN1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide; N,N’,N’’-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide; N,N’,N’’-Tris(β-hydroxyethyl)trimesamide;
Molecular WeightC15H21N3O6
Formula339.34
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsLM 22A4 is a potent tropomyosin-related kinase B (TrkB) agonist. LM 22A4 has been show to induce activation of Trk, Akt and ERK in mouse hippocampus and striatum and reverse deficits in motor task learning in mice following traumatic brain injury. LM 22A4 also restored respiratory function in a rat model of Rett syndrome.
ReferencesMassa, S.M. et al.: J. Clin. Invest., 120, 1774 (2010); Schmid, D.A. et al.: J. Neurosci., 32, 1803 (2012);
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LM 22A4
Price(USD)
SizePrice(USD)Discount
50mg$140.0010% OFF
5g$1750.0010% OFF
500mg$1120.0010% OFF
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