LGX 818

Catalogue number C241451
Chemical nameLGX 818
CAS Number1269440-17-6
SynonymsN-[(1S)-2-[[4-[3-[5-Chloro-2-fluoro-3-[(methylsulfonyl)amino]phenyl]-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-1-methylethyl]-carbamic Acid Methyl Ester; (S)-Methyl [1-[[4-[3-[5-chloro-2-fluoro-3-(methylsulfonamido)phenyl]-1-isopropyl-1H-pyr
Molecular WeightC22H27ClFN7O4S
Formula540.01
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsLGX 818 is potent and selective BRAFV600E kinase inhibitor and can be used for the treatment of proliferative diseases such as solid tumor diseases.
ReferencesHuang, T., et al.: J. Hematol. Oncol., 6, 30 (2013); Stuart, D., et al. Method of treating a proliferative disease with a BRAF kinase inhibitor. PCT Int. Appl. WO 2013070996 A1 20130516. May 16, 2013
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LGX 818
Price(USD)
SizePrice(USD)Discount
.5mg$85.0010% OFF
5mg$350.0010% OFF
1mg$150.0010% OFF
25mg$1375.0010% OFF
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