| Catalogue number | C241292 |
| Chemical name | LEE011 Succinate |
| CAS Number | 1374639-75-4 |
| Synonyms | 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide Succinate |
| Molecular Weight | C27H36N8O5 |
| Formula | 552.63 |
| Purity | 98% |
| Physical Description | Pale Beige Solid |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models. |
| References | Kim, S., et al.: Mol. Cancer Ther., 12, PR02 (2013); Rader, J., et al.: Clin. Cancer Res., 19, 6173 (2013) |
| Guestbook |
After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Featured Products
| C108535 | Isochlorogenic acid B | $110.00/20mg |
| C253620 | Pinoresinol Diglucoside | $98.00/20mg |
| C108848 | Ginsenoside Rh3 | $134.00/5mg |
| C108534 | Isochlorogenic acid A | $110.00/20mg |
| C104149 | Sophoraflavanone G | $150.00/10mg |
Price(USD)
| Size | Price(USD) | Discount |
| 2.5mg | $150.00 | 10% OFF |
| 50mg | $1125.00 | 10% OFF |
| 10mg | $275.00 | 10% OFF |
Orders by E-mail
Orders can be placed by Emails. All orders received will be shipped in the next day if the stock is available.
To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
To place an order, please provide the following information.
1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses
Sent to your order to our email: info@coompo.com
Discount Request
If you have any questions about discounts or dealer discount, please send us a message. We will be glad to help.
