JNJ-7706621

Catalogue number C240541
Chemical nameJNJ-7706621
CAS Number443797-96-4
SynonymsN3-[4-(Aminosulfonyl)phenyl]-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazole-3,5-diamine; 4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-yl]amino]benzenesulfonamide; JNJ 770662;
Molecular WeightC15H12F2N6O3S
Formula394.36
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsJNJ-770662 is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. JNJ-770662 has been shown to induce growth suppression and mitotic defects, these results suggest that JNJ-7706621 could be useful for cell cycle analysis and therapy of various cancers, including Ewing’s sarcoma.
ReferencesMatsuhashi, A. et al.: Curr. Cancer Drug Tar., 12, 625 (2012); Emanue,l S. et al.: Cancer Res., 65, 9038 (2005); Seamon, J.A. et al.: Mol. Cancer Ther., 5, 2459 (2006);
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JNJ-7706621
Price(USD)
SizePrice(USD)Discount
2mg$95.0010% OFF
10mg$320.0010% OFF
100mg$1250.0010% OFF
5mg$175.0010% OFF
50mg$825.0010% OFF
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