J 147

Catalogue number C240497
Chemical nameJ 147
CAS Number1146963-51-0
Synonyms2,2,2-Trifluoroacetic Acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl) methylene]hydrazide;
Molecular WeightC18H17F3N2O2
Formula350.33
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsJ 147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer’s disease. J 147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer’s disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.
ReferencesChen, J., et al.: J. Neurosci., 25, 2366 (2005), Maher, P., et al.: Brain Res., 1173, 117 (2007), Liu, Y., et al.: J. Neurochem., 105, 1336 (2008), Herrup, K., et al.: J. Neurosci., 30, 16755 (2010);
Guestbook
  Fill your Email(mail@mail.com)  
After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Featured Products
C101167Arteannuin B$230.00/20mg
C103863Ganoderic acid DM$474.00/5mg
C108469Tenuifolin$110.00/20mg
C253620Pinoresinol Diglucoside$98.00/20mg
C108812Ginsenoside Compound K$126.00/20mg
J 147
Price(USD)
SizePrice(USD)Discount
1mg$45.0010% OFF
10mg$150.0010% OFF
1g$1175.0010% OFF
5mg$125.0010% OFF
50mg$575.0010% OFF
Orders by E-mail
Orders can be placed by Emails. All orders received will be shipped in the next day if the stock is available.

To place an order, please provide the following information.

1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses

Sent to your order to our email: info@coompo.com
Discount Request
If you have any questions about discounts or dealer discount, please send us a message. We will be glad to help.
Go directly to Coompo product type beginning with
ABC
DEF
GHI
JKL
MNO
PQR
STU
VWX
YZ
  • Contact Us

  •  
  • Email: info@coompo.com
  • Tel: +86-27-84396673
  •  
  • Building B, No.77 Chuangye Rd,
  • Wuhan Economic and Technological Development Zone,
  • Hubei 430056, PRC
  • ©2013-2021 Coompo  |  All rights reserved.