Intedanib N-β-D-Glucuronide

Catalogue number C244119
Chemical nameIntedanib N-β-D-Glucuronide
CAS NumberN/A
Synonyms(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester N-β-D-Glucuronide; BIBF 1120 N-β-D-Glucuronide; Ofev N-β-D-Glucuronide; Vargatef N-β-D-G
Molecular WeightC36H38N5O10
Formula701.72
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsIntedanib N-β-D-Glucuronide is a possible metabolite of Intedanib (I666650), an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.
ReferencesSun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)
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Intedanib N-β-D-Glucuronide
Price(USD)
SizePrice(USD)Discount
1mg$225.0010% OFF
5mg$950.0010% OFF
2.5mg$500.0010% OFF
10mg$1800.0010% OFF
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