Catalogue number | C239615 |
Chemical name | IQ 1 |
CAS Number | 331001-62-8 |
Synonyms | 2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide; 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)acetamide; |
Molecular Weight | C21H22N4O2 |
Formula | 362.42 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | IQ 1 disrupts Wnt signaling. IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription. |
References | Kanai., et al.: The Pharmacogenomics J., 4, 336 (2004), Miki., et al.: Stem Cells, 23, 1549 (2005), T. Miyabayashi, et al.: Proc. Natl. Acad. Sci., 104, 5668 (2007), Luo., et al.: Ann. Neurol., 65, 520 (2009), |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
Size | Price(USD) | Discount |
10mg | $140.00 | 10% OFF |
100mg | $1120.00 | 10% OFF |
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To place an order, please provide the following information.
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Sent to your order to our email: info@coompo.com
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