Hyptadienic acid

Catalogue number C101452
Chemical nameHyptadienic acid
CAS Number128397-09-1
SynonymsA(1)-Norursa-2,12-dien-28-oicacid, 19-hydroxy-2-(hydroxymethyl)-; (+)-Hyptadienic acid; Coleonolic acid
Molecular WeightC30H46O4
Formula470.7
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsTheir anti-inflammatory and antitumor-promoting effects.
Hyptadienic acid isolated from the plant extract exhibited moderate cytotoxicity against HepG2 cells.
Hyptadienic acid is the active principles responsible for the cytotoxicity against three cultured human tumor cell lines, HL-60 (leukemia carcinoma), MCF-7 (breast carcinoma), and Hep-G2 (hepatic carcinoma), with half maximal inhibitory concentration (IC50) values of 12–48 μM.
References1. Pharmaceutical Biology, 2003, 41(5) , 375-378.
2. Phytochemistry, 2002, 59(3), 315-323.
3. Journal of Natural Medicines, 2006, 60(4), 331-333.
4. Natural Product Research, 2008, 22(12), 1067-1073.
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Hyptadienic acid
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