Hypaconitine

Catalogue number C108656
Chemical nameHypaconitine
CAS Number6900-87-4
Synonyms(1-alpha,6-alpha,14-alpha,15-alpha,16-beta)-acetatebenzoat;15-tetraol,16,16-trimethoxy-4-(methoxymethyl)-20-methyl-18-aconitane-14;(1α,6α,14α,15α,16β)1,6,16-TriMethoxy-4-(MethoxyMethyl)-20-Methylaconitane-8,13,14,15-tetrol 8-Acetate 14-Benzoate
Molecular WeightC33H45NO10
Formula615.7
Purity98%
Physical DescriptionWhite powder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

The neuromuscular blocking actions of several constituents extracted from Japanese-sino medicine, aconite, were compared in mouse phrenic nerve-diaphragm muscle preparations. Hypaconitine (HAT) was more potent than aconitine (ATN), mesaconitine (MAT) and deoxyaconitine. Aconite action is dependent on HAT, a main constituent.


The neuromuscular blockade produced by hypaconitine and aconitine were caused by reducing the evoked quantal release. The mechanism of this effect was attributed mainly to blocking of the nerve compound action potential.

References1. Chem. Pharm. Bull., 1983, 31(8), 2884-2886.
2. Chemistry of Natural Compounds, 1985, 21(5), 678-679.
3. Molecules, 2012, 17(5), 5187-5194.
Guestbook
  Fill your Email(mail@mail.com)  
After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Featured Products
C108707Wogonoside$80.00/20mg
C101411Ganoderol B$294.00/5mg
C1042803-O-Feruloylquinic acid$422.00/5mg
C253620Pinoresinol Diglucoside$98.00/20mg
C103886Morusinol$334.00/5mg
Hypaconitine
Price(USD)
SizePrice(USD)Discount
5mgInquiryN/A
10mgInquiryN/A
25mgInquiryN/A
Orders by E-mail
Orders can be placed by Emails. All orders received will be shipped in the next day if the stock is available.

To place an order, please provide the following information.

1) Your name and telephone number
2) Purchase order number
3) Product number, package size, description, and quantity
4) Shipping and billing addresses

Sent to your order to our email: info@coompo.com
Discount Request
If you have any questions about discounts or dealer discount, please send us a message. We will be glad to help.
Go directly to Coompo product type beginning with
ABC
DEF
GHI
JKL
MNO
PQR
STU
VWX
YZ
  • Contact Us

  •  
  • Email: info@coompo.com
  • Tel: +86-27-84396673
  •  
  • Building B, No.77 Chuangye Rd,
  • Wuhan Economic and Technological Development Zone,
  • Hubei 430056, PRC
  • ©2013-2021 Coompo  |  All rights reserved.