| Catalogue number | C108774 |
| Chemical name | Ginsenoside Rg1 |
| CAS Number | 22427-39-0 |
| Synonyms | (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]hept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta |
| Molecular Weight | C42H72O14 |
| Formula | 801.0 |
| Purity | 98% |
| Physical Description | White powder |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | Ginsenosides have demonstrated pharmacological effects in the central nervous, cardiovascular, and endocrine systems. Ginsenoside-Rg1 (G-Rg1) acts by binding to the glucocorticoid receptor (GR). G-Rg1 competed for [3H]dexamethasone (Dex) binding to GR with a specific affinity of 1-10 microM and activated a glucocorticoid responsive element-containing luciferase reporter gene. The dose-dependence patterns of G-Rg1 and Dex for these two effects were nearly identical, although two to three orders of magnitude higher concentration of G-Rg1 than that of Dex was required for the same magnitude of response. At the cellular level, the growth of FT02B cells was suppressed by G-Rg1 as well as by Dex, each of whose effects were abolished by RU486. These results demonstrate that G-Rg1 is a functional ligand of GR.
Ginsenosides Rg1 has estrogen-like activity and should be classified as a novel class of potent phytoestrogen.
Ginsenoside-Rg1 is an interesting substance. In cell and animal studies it has been shown to boost the production of insulin receptors; it stimulates the creation of new blood vessels and wound healing; relaxes and widens blood vessels and lowers blood pressure.
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| References | 1. Mol Cell Endocrinol., 1997, 133(2), 135-140. 2. J. Clin. Endocrinol Metab., 2002, 87(8), 3691-3695. 3. Acta Pharmacol Sin., 2008, 29(9), 1103-1108. |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
| Size | Price(USD) | Discount |
| 5mg | Inquiry | N/A |
| 10mg | Inquiry | N/A |
| 25mg | Inquiry | N/A |
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To place an order, please provide the following information.
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Sent to your order to our email: info@coompo.com
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