| Catalogue number | C108849 |
| Chemical name | Ginsenoside Rc |
| CAS Number | 11021-14-0 |
| Synonyms | 2-[[2-[[17-[2-[[6-[[3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]oxymethyl]-3,4,5-trihydroxy-2-oxanyl]oxy]-6-methylhept-5-en-2-yl]-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4,5-dihydro |
| Molecular Weight | C53H90O22 |
| Formula | 1079.2 |
| Purity | 98% |
| Physical Description | White powder |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | Ginsenoside-Rc was capable of inhibiting the growth of these cancer cells. This suggests that there is a possibility that ginsenoside-Rc may have effects that prevent or limit the development of breast cancer.
The consumption of ginsenoside-Rc had elongated the normal life span of the worm. Data from this experimentation showed a significant increase in motility when the sperm was in a ginsenoside-Rc solution.
Ginsenoside Rc significantly activated an insulin-independent AMPK signaling pathway. The activation of AMPK and p38 induced by ginsenosideRc is mediated by reactive oxygen species (ROS) production, suggesting that upstream regulators of AMPK- and p38 MAPK-mediated glucose uptake.
There is a significant variability in embryotoxic effects of different ginsenosides. Further studies to evaluate the synergistic embryotoxic effects of ginsenosides are warranted. |
| References | 1. Natural Product Sciences, 2008, 14(3), 171-176. 2. J. Ginseng Res., 2010, 34(2), 113-121. 3. Zhongguo Zhong Yao Za Zhi, 2003, 28, 828-830. 4. Chem. Pharm. Bull., 1989, 37(11), 2961-2970. 5. Journal of Ethnopharmacology, 2010, 127(3), 771-776. |
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