| Catalogue number | C108854 |
| Chemical name | Ginsenoside F3 |
| CAS Number | 62025-50-7 |
| Synonyms | (20S)-20-(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyloxy)-5α-dammara-24-ene-3β,6α, 12β-triol;3β,6α,12β-Trihydroxy-5α-dammar-24-en-20-yl 6-O-α-L-arabinopyranosyl-β-D-glucopyranoside |
| Molecular Weight | C41H70O13 |
| Formula | 770.9 |
| Purity | 98% |
| Physical Description | White powder |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | The enhancing effect of ginsenoside-F3 on murine spleen cell proliferation was studied using [3H]thymidine incorporation assay. Effects of ginsenoside-F3 on the production of type 1 cytokines IL-2, IFN-γ, and type 2 cytokines IL-4 and IL-10 from murine spleen cells were detected by ELISA method. Effects of ginsenoside-F3 on mRNA level of cytokines IL-4, IFN-γ, and transcription factors T-bet and GATA-3 were evaluated by RT-PCR analysis. Effect of ginsenoside-F3 on NF-κB DNA binding activity in murine spleen cells was investigated by electrophoretic mobility shift assays (EMSA). Ginsenoside-F3 at 0.1-100 µmol/L not only promoted the murine spleen cell proliferation, but also increased the production of IL-2 and IFN-γ, while decreased the production of IL-4 and IL-10 from murine spleen cells with the maximal effect at 10 µmol/L. RT-PCR analysis displayed that ginsenoside-F3 enhanced the IFN-γ and T-bet gene expression and decreased IL-4 and GATA-3 gene expression. EMSA experiment showed that ginsenoside-F3 10 µmol/L enhanced the NF-κB DNA binding activity induced by ConA in murine spleen cells. Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1 cytokines and type 2 cytokines in murine spleen cells. |
| References | 1. Acta Pharmacol Sin., 2004, 25(12), 1671-1676. 2. Food Science and Biotechnology, 2010, 19(4), 1119-1122. 3. Chemical and Pharmaceutical Bulletin, 2013, 61(3), 273-278. |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Price(USD)
| Size | Price(USD) | Discount |
| 10mg | $185.00 | 5% OFF |
| 20mg | $315.00 | 8% OFF |
| 50mg | $724.00 | 15% OFF |
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To place an order, please provide the following information.
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Sent to your order to our email: info@coompo.com
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