Ganoderic acid DM

Catalogue number C103863
Chemical nameGanoderic acid DM
CAS Number173075-45-1
SynonymsGaderic acid DM; 3,7-Dioxolanosta-8,24-dien-26-oic acid
Molecular WeightC30H44O3
Formula452.7
Purity98%
Physical DescriptionPowder
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
Applications

Ganoderic acid DM (GADM), with 5α-reductase inhibitory and androgen receptor (AR) binding activity, can inhibit prostate cancer cell growth and block osteoclastogenesis.


GADM effectively inhibited cell proliferation and colony formation in MCF-7 human breast cancer cells, which was much stronger than that of MDA-MB-231 breast cancer cells. GADM elicited DNA damage as measured by comet assay which is a sensitive method for DNA damage detection.

References1. Yaoxue Xuebao, 1997, 32, 447-450.
2. Fitoterapia, 2012, 83 (2), 408-414.
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Ganoderic acid DM
Price(USD)
SizePrice(USD)Discount
5mg$474.005% OFF
10mg$806.008% OFF
25mg$1370.0015% OFF
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