GSK 5072 Dihydrochloride

Catalogue number C239412
Chemical nameGSK 5072 Dihydrochloride
CAS NumberN/A
Synonyms5-(((4-Chlorobenzyl)(pyridin-3-ylmethyl)amino)methyl)thiophene-2-carbonitrile Dihydrochloride; 5-[[[(4-Chlorophenyl)methyl](3-pyridinylmethyl)amino]methyl]-2-thiophenecarbonitrile Dihydrochloride
Molecular WeightC18H16ClN3S2.HCl
Formula353.8736462
Purity98%
Physical DescriptionOff-White to Pale Yellow Solid
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsGSK 5072 Dihydrochloride, is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.
ReferencesKojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)
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GSK 5072 Dihydrochloride
Price(USD)
SizePrice(USD)Discount
10mg$120.0010% OFF
100mg$960.0010% OFF
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