Catalogue number | C236651 |
Chemical name | GGTI-2147 |
CAS Number | 191102-87-1 |
Synonyms | N-[4-[(1H-Imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-L-leucine Methyl Ester; GGTI 2147 |
Molecular Weight | C28H30N4O3 |
Formula | 470.56 |
Purity | 98% |
Physical Description | Powder |
Solvent | Chloroform, Dichloromethane,DMSO |
Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
Applications | GGTI-2147 is an inhibitors of protein geranylgeranyltransferase-I and protein prenylation. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast and increases cytosolic accumulation of Rac1 and elicites significant inhibition of GSIS from INS 832/13 cells. |
References | Chang, S. et al.: J. Lipid. Res., 53, 1176 (2012); Veluthakal, R. et al.: Diabetes., 56, 204 (2007) |
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After Receiving
The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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5mg | $1400.00 | 10% OFF |
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