Epifriedelanol

Catalogue number C107842
Chemical nameEpifriedelanol
CAS Number16844-71-6
Synonyms(3S,4R,4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a-octamethyl-1,2,3,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-hexadecahydropicen-3-ol
Molecular WeightC30H52O
Formula428.7
Purity98%
Physical DescriptionCryst.
SolventChloroform, Dichloromethane,DMSO
StorageStored at 2-8°C, Protected from air and light, refrigerate or freeze
ApplicationsEpifriedelanol had inhibitory effects on adriamycin-induced cellular senescence in human fibroblasts (HDFs). Epifriedelanol suppressed adriamycin-induced cellular senescence as well as replicative senescence in human fibroblasts (HDFs) and human umbilical vein endothelial cells (HUVECs). These results suggest that epifriedelanol reduces cellular senescence in human primary cells and might be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases.
Epifriedelanol demonstrated antitumor activity in a potato disc bioassay.
References1. Fitoterapia, 2000, 71(5), 577-579.
2. Planta Med., 2011, 77(5), 441-449.
3. Phytochemistry, 1998, 49(4), 1115-1118.
4. Journal of Pharmaceutical Sciences, 1971, 60(12), 1891-1892.
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Epifriedelanol
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SizePrice(USD)Discount
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10mgInquiryN/A
25mgInquiryN/A
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