| Catalogue number |
C101311 |
| Chemical name | Dehydroabietic acid |
| CAS Number | 1740-19-8 |
| Synonyms | (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid |
| Molecular Weight | C20H28O2 |
| Formula | 300.4 |
| Purity | 98% |
| Physical Description | Oil |
| Solvent | Chloroform, Dichloromethane,DMSO |
| Storage | Stored at 2-8°C, Protected from air and light, refrigerate or freeze |
| Applications | EBV-EA activation inhibitor.
Dehydroabietic acid derivatives have been reported to display antisecretory and antipepsin effect in animal models.
20 μg l−1 is close to the “minimum effective concentration” of Dehydroabietic acid to rainbow trout.
Dehydroabietic acid (DAA) treatment decreased not only plasma glucose and insulin levels but also plasma triglyceride (TG) and hepatic TG levels. To examine the mechanism underlying the effects of DAA, the production of inflammatory cytokines was measured. It was shown that the DAA treatment suppressed the production of monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-alpha (TNFalpha) (proinflammatory cytokines) and increased that of adiponectin (an anti-inflammatory cytokine). As a result of the changes in the production of inflammatory cytokines caused by the DAA treatment, the accumulation of macrophages in adipose tissues was reduced. These results indicate that treatment with DAA improves the levels of plasma glucose, plasma insulin, plasma TG, and hepatic TG through the decrease in the macrophage infiltration into adipose tissues, suggesting that DAA is a useful food-derived compound for treating obesity-related diseases.
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| References | 1. Tet. Lett., 1968, 1565.
2. Biofactors., 2009, 35(5), 442-448.
3. European Journal of Medicinal Chemistry, 2010, 45, 811-816.
4. Water Research, 1983, 17(1), 81-89.
5. Pharmacological Research, 2005, 52(5), 429-437.
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The packaging of the product may have turned upside down during transportation, resulting in the product adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
| Size | Price(USD) | Discount |
| 5mg | Inquiry | N/A |
| 10mg | Inquiry | N/A |
| 25mg | Inquiry | N/A |
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